Stanford Home
Ovarian Kaleidoscope Database (OKdb)

Home

History

Transgenic Mouse Models

INFORGRAPHICS

Search
Submit
Update
Chroms
Browse
Admin

Hsueh lab

HPMR

Visits
since 01/2001:
176557

G protein-coupled receptor 68 OKDB#: 1273
 Symbols: GPR68 Species: human
 Synonyms: OGR1, AI2A6, GPR12A  Locus: 14q32.11 in Homo sapiens
HPMR


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
Mammalian Reproductive Genetics   Endometrium Database Resource   Orthologous Genes   UCSC Genome Browser   GEO Profiles new!   Amazonia (transcriptome data) new!

R-L INTERACTIONS   MGI

DNA Microarrays
SHOW DATA ...
link to BioGPS
General Comment GPR68 Senses Flow and Is Essential for Vascular Physiology. A Mechanosensitive GPCR that Detects the Bloody Force. CELL 2018 Xu and Casey (1996) described a gene encoding a member of the G protein-coupled receptors that they termed ovarian cancer G protein-coupled receptor-1 (OGR1). It was isolated by degenerate PCR from an ovarian cell line cDNA library.

NCBI Summary: The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]
General function Receptor
Comment
Cellular localization Plasma membrane
Comment
Ovarian function Tumorigenesis
Comment
Expression regulated by
Comment
Ovarian localization Oocyte
Comment goes up in a follicle stage-dependent manner in oocytes
Follicle stages Antral, Preovulatory
Comment
Phenotypes
Mutations 0 mutations
Genomic Region show genomic region
Phenotypes and GWAS show phenotypes and GWAS
Reprogenomic viewer show phenotypes and GWAshow RNAseq data and genomic region in Reprogenomic viewer site
(After opening the Reprogenomics Viewer site, select your gene and click on Chromosome + Link)
Links
OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
OMIM \ Animal Model
KEGG Pathways
Recent Publications
None
Search for Antibody
Discuss..
blog comments powered by Disqus
Related Genes
Beta
Show data ...


created: Aug. 28, 2001, 3:52 p.m. by: hsueh   email:
home page:
last update: April 20, 2018, 12:14 p.m. by: hsueh    email:



Use the back button of your browser to return to the Gene List.

Click here to return to gene search form