|Potassium Channel, Inwardly Rectifying, Subfamily J, Member 6||OKDB#: 3229|
|Synonyms:||BIR1, GIRK2, KATP2, KCNJ7, KIR3.2, hiGIRK2, MGC126596,GIRK2|POTASSIUM CHANNEL, INWARDLY RECTIFYING, SUBFAMILY J, MEMBER 7, FORMERLY, KCNJ7, FORMERLY||Locus:||21q22.1 in Homo sapiens|
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R-L INTERACTIONS MGI
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NCBI Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
|Ovarian function||Oogenesis, Oocyte maturation|
|Comment||Gene whose expression is detected by cDNA array hybridization: oncogenes, tumor suppressors, cell cycle regulators Rozenn Dalbis-Tran and Pascal Mermilloda|
|Expression regulated by|
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|Phenotypes and GWAS||show phenotypes and GWAS|
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|created:||June 22, 2006, 11:14 a.m.||by:||
|last update:||July 25, 2006, 2:54 p.m.||by:||Alex email:|
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