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Ovarian Kaleidoscope Database (OKdb)

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HPMR

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Potassium Channel, Inwardly Rectifying, Subfamily J, Member 6 OKDB#: 3229
 Symbols: KCNJ6 Species: human
 Synonyms: BIR1, GIRK2, KATP2, KCNJ7, KIR3.2, hiGIRK2, MGC126596,GIRK2|POTASSIUM CHANNEL, INWARDLY RECTIFYING, SUBFAMILY J, MEMBER 7, FORMERLY, KCNJ7, FORMERLY  Locus: 21q22.1 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: OMIM Entrez Gene
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General Comment

NCBI Summary: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex.
General function
Comment
Cellular localization
Comment
Ovarian function Oogenesis, Oocyte maturation
Comment Gene whose expression is detected by cDNA array hybridization: oncogenes, tumor suppressors, cell cycle regulators Rozenn Dalbis-Tran and Pascal Mermilloda
Expression regulated by
Comment
Ovarian localization
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
SNPs
D E M O
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OMIM (Online Mendelian Inheritance in Man: an excellent source of general gene description and genetic information.)
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created: June 22, 2006, 11:14 a.m. by: alex   email:
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last update: July 25, 2006, 2:54 p.m. by: Alex    email:



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