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Ovarian Kaleidoscope Database (OKdb)

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Hsueh lab

HPMR

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since 01/2001:
176557

squamous cell carcinoma antigen recognised by T cells 3 OKDB#: 3631
 Symbols: SART3 Species: human
 Synonyms: TIP110, KIAA0156, MGC138188, p110(nrb), RP11-13G14,  Locus: 12q24.1 in Homo sapiens


For retrieval of Nucleotide and Amino Acid sequences please go to: Entrez Gene
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General Comment

NCBI Summary: The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
General function
Comment
Cellular localization Nuclear
Comment
Ovarian function
Comment
Expression regulated by
Comment
Ovarian localization Oocyte
Comment
Follicle stages
Comment
Phenotypes
Mutations 0 mutations
SNPs
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created: Oct. 30, 2006, 4:44 p.m. by: amazinmazin   email:
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last update: Oct. 30, 2006, 4:44 p.m. by: amazinmazin    email:



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