|squamous cell carcinoma antigen recognised by T cells 3||OKDB#: 3631|
|Synonyms:||TIP110, KIAA0156, MGC138188, p110(nrb), RP11-13G14,||Locus:||12q24.1 in Homo sapiens|
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NCBI Summary: The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.
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|Phenotypes and GWAS||show phenotypes and GWAS|
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|created:||Oct. 30, 2006, 4:44 p.m.||by:||
|last update:||Oct. 30, 2006, 4:44 p.m.||by:||amazinmazin email:|
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